Abstract: This ad hoc analysis, based on studies identified from a systematic review of e-cigarette emissions, synthesized evidence from 13 emission studies that directly compared NNK and NNN levels between e-cigarette aerosols and cigarette smoke. The results suggest that switching to exclusive e-cigarette use can lead to a significant reduction in exposure to key tobacco-specific nitrosamines. This study also reinforces the importance of articulating this evidence with clarity, precision, and balance, recognizing both the substantial benefits of reduced exposure and the residual uncertainties that only long-term studies will resolve.
https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2025.1729107/full
