Nicotine is an addictive substance, but the primary health risks associated with smoking come from the toxic byproducts of combustible tobacco. A substantial body of evidence shows that nicotine can be delivered through smoke-free alternatives as part of a harm reduction approach to smoking cessation.
Learn more in this evidence brief from Action on Smoking and Health; https://ash.org.uk/uploads/ASH-evidence-brief-on-nicotine-V6-Nov25.pdf?v=1766154227